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(Cheson BD, Fisher RI, Barrington SF, Cavalli F, Schwartz LH, Zucca E, Lister TA; Alliance, Australasian Leukaemia and Lymphoma Group; Eastern Cooperative Oncology Group; European Mantle Cell Lymphoma Consortium; Italian Lymphoma Foundation; …
Oncology Institute of Southern Switzerland (IOSI), ESMO E-Learning: The Lugano Classification recommendations for Hodgkin’s and non-Hodgkin’s lymphoma: Staging, Response Assessment and Follow Up, The Lugano Classification Recommendations for Hodgkin's and non-Hodgkin's lymphoma, Interpreting Oncological Study Publications, Cancer Diagnosis and Treatment Evaluation, Rehabilitation Issues During Cancer Treatment and Follow-Up, Cancer Treatment in Special Clinical Situations, Clinical Pharmacology of Anti-Cancer Agents, Curriculum in Translational Research in Breast Cancer, International Prognostic Index Tools for Lymphoma, Anti-Cancer Agents and Biological Therapy, Drug-Drug Interactions with Kinase Inhibitors, PARP inhibition and DNA Damage Response (DDR), Cancer Aetiology, Epidemiology and Prevention, Cancer in Special situations (pregnancy, young, elderly, hereditary...), Multikinase Inhibitor-Related Skin Toxicity, Precision Medicine and Validated Biomarkers, Translational Research: Biomarkers & Diagnostics, ESMO E-Learning: The Lugano Classification Recommendations For Hodgkin's and non-Hodgink's Lymphoma - Staging Response Assessment and Follow Up, ESMO-MORA Recertification Process and Requirements, Role of PET in Staging and Treatment of Lymphomas, The History of Lymphoma Classification and the 2016 WHO Revision, To provide an update on the latest Lugano classification with recommendations for staging, response assessment and follow-up in patients with lymphomas, To enhance the application of the latest recommendations for staging, response assessment and follow-up in lymphoma and improve the findings interpretation in clinical practice and late phase clinical trials, To improve standardization of staging, response assessment and follow-up in lymphoma patients.
The recommendations were made through a dedicated work and broad consultation of experts from different international cancer centres and lymphoma clinical trial groups; in particular Alliance, Australasian Leukaemia and Lymphoma Group, Eastern Cooperative Oncology Group, European Mantle Cell Lymphoma Consortium, Italian Lymphoma Foundation, European Organisation for Research and Treatment of Cancer/Dutch Hemato-Oncology Group, Grupo Español de Linfomas y Trasplantes de Médula Ósea, German High-Grade Lymphoma Study Group, German Hodgkin's Study Group, Japanese Lymphoma Study Group, Lymphoma Study Association, NCIC Clinical Trials Group, Nordic Lymphoma Study Group, Southwest Oncology Group, and UK National Cancer Research Institute. It is imperative that we remember the provisional nature of these proposed changes and actively participate in their refinement.”2, Contact Us | Terms of Service | Privacy Policy. Through a series of educational slides, the authors of this module present what is new in revised classification in terms of initial evaluation, staging criteria, prognostic groups, response assessment, follow-up and surveillance. Some of these cookies are essential, while others help us improve your experience by providing insights into how the site is being used. This site uses cookies. endstream
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“This will allow patients to continue what may be beneficial therapy and the generation of data that can be analyzed to determine whether this strategy of treatment past IR does indeed confer a clinical benefit.”, “Physicians need to be aware of this possibility when using drugs with the potential for a flare,” Dr. Cheson told ASH Clinical News. Unless this phenomenon is recognized, patients may be taken off a drug that is actually effective. Staging and response criteria were initially developed for Hodgkin lymphoma (HL) over 60 years ago, but not until 1999 were response criteria published for non-HL (NHL). [Epub ahead of print]. “This follows several potential patterns: an increase in the size of lesions, the development of new lesions despite regression of the initial lesions, or increased F-fluorodeoxyglucose (FDG)-avidity despite no change in lesion size. Rethinking clinical response and outcome assessment in a biologic age. USA.gov. © 2016 by The American Society of Hematology. Staging. 2015.
National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Thus, we have introduced IR, which is assigned to patients until a subsequent scan distinguishes response from progressive disease.”. & the Lugano Classification SF Barrington, NG Mikhaeel, L Kostakoglu, M Meignan, ... To update 2007 IHP imaging & response criteria in lymphoma For use in clinical practice and late phase trials ICML IMAGING GUIDELINES & THE LUGANO CLASSIFICATION Barrington SF et al JCO in press Cheson BD et al JCO in press . Also, the value of the provisional "minor response" (MiR) category of RECIL is unclear. Limited. Please enable it to take advantage of the complete set of features! Considering this finding as PD could lead to patients being prematurely removed from a treatment from which they actually stand to benefit. Is the lymphoma better? This site needs JavaScript to work properly. Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. MINIMAL Requirements: Google Chrome 24+, Mozilla Firefox 20+, Internet Explorer 11, Opera 15–18, Apple Safari 7, SeaMonkey 2.15-2.23. Staging and response criteria were initially developed for Hodgkin lymphoma (HL) over 60 years ago, but not until 1999 were response criteria published for non-HL (NHL).
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Since the first internationally accepted response criteria, the Lugano Classification Response Criteria, were published in 1999, advances in immunomodulatory therapies that affect imaging interpretation have resulted in the need for revised criteria for staging and response. 2016;128:2481-82. To address this issue in the context of lymphoma immunomodulatory therapy, a workshop was convened to provide provisional recommendations to modify current response criteria in patients receiving these and future agents in clinical trials. The Lugano staging classification is the lymphoma staging system that is most commonly used in clinical practice currently. Blood. 2015;2015:69-73. doi: 10.1182/asheducation-2015.1.69.
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