A recent case study has shown a possible increase in the plasma level of valproate when co-administered with isoniazid. 0000061904 00000 n Do not flush down a toilet or pour down a drain unless you are told to do so. Advanced technologies. This medicine may also interact with the following medications: medicines for fungal infections like ketoconazole and itraconazole, medicines for seizures like carbamazepine, phenobarbital, phenytoin, valproic acid. Follow the directions on the prescription label. Abstract. Do not take double or extra doses. It will open today at 12:00PM. You may report side effects to the FDA at 1-800-332-1088.

If you are diabetic check your blood sugar as directed.

Take on an empty stomach. Isoniazid Syrup Isoniazid Syrup Description. Isoniazid is chemically known as isonicotinyl hydrazine or isonicotinic acid hydrazide.

If the bacilli becomes resistant, therapy must be changed to agents to which the bacilli are susceptible.

Isoniazid oral solution USP is available as a clear, peppermint-lime flavored solution containing 50 mg isoniazid per 5 mL. Adults over 30 kg: 300 mg per day in a single dose. 0000019612 00000 n Agranulocytosis; hemolytic, sideroblastic or aplastic anemia, thrombocytopenia; and eosinophilia. For following patient compliance: the Potts-Cozart test9, a simple colorimetric6 method of checking for isoniazid in the urine, is a useful tool for assuring patient compliance, which is essential for effective tuberculosis control. However, slow acetylation may lead to higher blood levels of the drug and, thus, to an increase in toxic reactions.

Mild hepatic dysfunction, evidenced by mild and transient elevation of serum transaminase levels occurs in 10 to 20 percent of patients taking isoniazid. Because of the insufficient data, miliary tuberculosis, bone/joint tuberculosis and tuberculous meningitis in infants and children should receive 12 month therapy. 15 mg/kg up to 900 mg/day, two or three times/week.

Do not store in your bathroom or kitchen, as heat and moisture may cause the drug to be less active. If isoniazid therapy must be reinstituted, the drug should be given only after symptoms have cleared. Each 5 mL (teaspoonful) of syrup contains 50 mg of isoniazid.

Other factors associated with an increased risk of hepatitis include daily use of alcohol, chronic liver disease and injection drug use. June 25, 2018.

0000102369 00000 n problems, or injection drug use.
Isoniazid is retained in the skin and in infected tissue; it crosses the placenta and is secreted in the milk of lactating mothers.

ISONIAZID (eye soe NYE a zid) is used to prevent or to treat tuberculosis.

Keep all drugs out of the reach of children and pets.
32 65

20 mg/kg to 40 mg/kg up to 900 mg/day, two or three times/week.

Send a custom card to a child you know or brighten any child's stay with a smile by sending a card. Isoniazid tablets and syrup should be stored in a cool (15-25 oC) dry place, protected from light and well out of the reach of children.

with your doctor, nurse, pharmacist, or other health care provider.

Phenytoin should be used cautiously, because isoniazid interferes with the metabolism of phenytoin. Skipping doses may make the TB resistant to this medicine and other medicines.

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